Proteintech, 98318-1-RR, Anti-Human CD63 Rabbit Recombinant Antibody

Size: 100ug The CD63 (98318-1-RR) by Proteintech is a Recombinant antibody targeting CD63 in FC applications with reactivity to human samples 98318-1-RR targets CD63 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: Thrombin treated human peripheral blood platelets Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD63 is a 30-60 kDa lysosomal membrane protein that belongs to the tetraspanin family. This protein plays many important roles in immuno-physiological functions. It mediates signal transduction events that regulate cell development, activation, growth, and motility. CD63 is expressed on activated platelets, thus it may function as a blood platelet activation marker. CD63 is a lysosomal membrane glycoprotein translocated to the plasma membrane after platelet activation. The CD63 tetraspanin is highly expressed in the early stages of melanoma and decreases in advanced lesions, suggesting it is a possible suppressor of tumor progression. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: CD63 molecule Calculated Molecular Weight: 26 kDa GenBank Accession Number: BC002349 Gene Symbol: CD63 Gene ID (NCBI): 967 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P08962 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.