Proteintech, 98345-2-RR, Anti-Human CD100 Rabbit Recombinant Antibody

Size: 100ug The CD100 (98345-2-RR) by Proteintech is a Recombinant antibody targeting CD100 in FC applications with reactivity to human samples 98345-2-RR targets CD100 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human PBMCs Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD100 (also known as SEMA4D), a 150 kDa homodimer, belongs to the family of immune semaphorins, and CD100 is abundantly expressed on resting T cells, NK cells, and antigen-presenting cells. As a transmembrane glycoprotein, it is digested to its soluble form, sCD100, by specific matrix metalloproteinases. CD100 has been reported that the expression levels of CD100, and one of its receptors, plexin-B1 (PLXNB1), are increased in head and neck, prostate, colon, breast, and lung cancers, and the interaction between them provides oncogenic signaling essential for tumor growth and metastasis. Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D Calculated Molecular Weight: 96 kDa GenBank Accession Number: BC054500 Gene Symbol: SEMA4D/CD100 Gene ID (NCBI): 10507 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q92854 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.