Proteintech, 98401-1-RR, Anti-Mouse TIM4 Rabbit Recombinant Antibody

Size: 100ug The TIM4 (98401-1-RR) by Proteintech is a Recombinant antibody targeting TIM4 in FC applications with reactivity to mouse samples 98401-1-RR targets TIM4 in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: mouse peritoneal macrophages Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information T cell immunoglobulin mucin 4 (TIM4) is a macrophage receptor for phosphatidylserine (PtdSer) on apoptotic cells. It is evidenced that TIM4 as phosphatidylserine (PS) receptor is capable of maintaining peritoneal macrophages' homeostatic function and regulating adaptive immunity based on the alteration of Ag-particular T cells' clearance. It is noteworthy that TIM4's dysregulating process was identified under several autoimmune states, in particular inside immune cells. In addition, TIM4 was identified to be over-expressed in Systemic lupus erythematosus (SLE) cases. Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg3307 Product name: Recombinant Mouse TIM4 protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 23-279 aa of NM_178759 Sequence: ASEDTIIGFLGQPVTLPCHYLSWSQSRNSMCWGKGSCPNSKCNAELLRTDGTRIISRKSTKYTLLGKVQFGEVSLTISNTNRGDSGVYCCRIEVPGWFNDVKKNVRLELRRATTTKKPTTTTRPTTTPYVTTTTPELLPTTVMTTSVLPTTTPPQTLATTAFSTAVTTCPSTTPGSFSQETTKGSAFTTESETLPASNHSQRSMMTISTDIAVLRPTGSNPGILPSTSQLTTQKTTLTTSESLQKTTKSHQINSRQT Predict reactive species Full Name: T-cell immunoglobulin and mucin domain containing 4 Calculated Molecular Weight: 38 kDa GenBank Accession Number: NM_178759 Gene Symbol: TIM4 Gene ID (NCBI): 276891 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q6U7R4 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.