Product Description
Size: 100ug
The CRTAM/CD355 (98420-3-RR) by Proteintech is a Recombinant antibody targeting CRTAM/CD355 in FC applications with reactivity to mouse samples
98420-3-RR targets CRTAM/CD355 in FC applications and shows reactivity with mouse samples.
Tested Applications
Positive FC detected in: Anti-CD3/CD28 treated mouse splenocytes
Recommended dilution
Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension
Background Information
Cytotoxic and regulatory T cell molecule (CRTAM, also known as CD355) is an immunoglobulin-superfamily transmembrane protein with V and C1-like Ig domains, which is involved in epithelial cell adhesion (PMID: 18329370; 20556794). CRTAM is critical to instruct the differentiation of CD4+ cytotoxic T cells (CTL) through the induction of eomesodermin and CTL-related genes (PMID: 26694968). It also regulates CD8+ T cell retention within the lymph node and eventually effector function (PMID: 19752223).
Specification
Tested Reactivity: mouse
Host / Isotype: Rabbit / IgG
Class: Recombinant
Type: Antibody
Immunogen: CatNo: Eg2691 Product name: Recombinant Mouse CRTAM/CD355 protein (rFc Tag) Source: mammalian cells -derived, V37 Tag: C-rFc Domain: 17-284 aa of NM_001281954.1 Sequence: AFLKMETVTVEEGQTLTLTCVTSQTKNVSLQWLAPSGFTIFLNQHPALKSSKYQLLHHSATQLSISVSNVTLREEGVYTCLHYGSSVKTKQVRVTVLVTPFQPTVEALVLRRQNGEKSVVLKCSTERSKPPPQITWLLGEGLEIYGELNHEFEADGKICNTSSMLIARAYGKNSTVHCIIQHEGLHGRKLVAPFQFEDLVADQETSDQETSDAPEQSSLSSQALQQPTSTVSMMENSSIPETDKEEKEHATQDPGLSTEASAQHTGLA Predict reactive species
Full Name: cytotoxic and regulatory T cell molecule
Calculated Molecular Weight: 44 kDa
GenBank Accession Number: NM_001281954.1
Gene Symbol: Crtam
Gene ID (NCBI): 54698
Conjugate: Unconjugated
Form: Liquid
Purification Method: Protein A purification
UNIPROT ID: Q149L7-1
Storage Buffer: PBS with 0.09% sodium azide, pH 7.3.
Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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