Proteintech, 98595-2-RR, Anti-Human CX3CL1 Rabbit Recombinant Antibody

Size: 100ug The CX3CL1 (98595-2-RR) by Proteintech is a Recombinant antibody targeting CX3CL1 in FC applications with reactivity to human samples 98595-2-RR targets CX3CL1 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: HepG2 cells Recommended dilution Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information CX3CL1, also known as fractalkine, is a transmembrane chemokine that acts as a ligand for both CX3CR1 and integrins αvβ3 and α4β1 (PMID: 9479488; 23125415). CX3CL1 is expressed by many hematopoietic and nonhematopoietic cells, including macrophages, endothelial cells, neurons, and fibroblasts. It is involved in immune responses and inflammation (PMID: 21045240). CX3CL1 exists in a membrane-anchored molecule and a soluble form, generated by proteolytic cleavage (PMID: 11495925; 12714508). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg6637 Product name: recombinant human CX3CL1 protein Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 25-341 aa of BC016164 Sequence: QHHGVTKCNITCSKMTSKIPVALLIHYQQNQASCGKRAIILETRQHRLFCADPKEQWVKDAMQHLDRQAAALTRNGGTFEKQIGEVKPRTTPAAGGMDESVVLEPEATGESSSLEPTPSSQEAQRALGTSPELPTGVTGSSGTRLPPTPKAQDGGPVGTELFRVPPVSTAATWQSSAPHQPGPSLWAEAKTSEAPSTQDPSTQASTASSPAPEENAPSEGQRVWGQGQSPRPENSLEREEMGPVPAHTDAFQDWGPGSMAHVSVVPVSSEGTPSREPVASGSWTPKAEEPIHATMDPQRLGVLITPVPDAQAATRRQ Predict reactive species Full Name: chemokine (C-X3-C motif) ligand 1 Calculated Molecular Weight: 42 kDa GenBank Accession Number: BC016164 Gene Symbol: CX3CL1 Gene ID (NCBI): 6376 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: P78423 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.