Proteintech, 98641-3-RR, Anti-Rat M-CSF Rabbit Recombinant Antibody

Size: 100ug The M-CSF (98641-3-RR) by Proteintech is a Recombinant antibody targeting M-CSF in FC (Intra) applications with reactivity to rat samples 98641-3-RR targets M-CSF in FC (Intra) applications and shows reactivity with rat samples. Tested Applications Positive FC (Intra) detected in: Transfected HEK-293T cells Recommended dilution Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information M-CSF plays an essential role in the regulation of survival, proliferation and differentiation of hematopoietic precursor cells, especially mononuclear phagocytes. M-CSF promotes the release of proinflammatory chemokines, and thereby plays an important role in innate immunity and in inflammatory processes. It also plays an important role in the regulation of osteoclast proliferation and differentiation, the regulation of bone resorption, and is required for normal bone development. On the cellular level, M-CSF promotes reorganization of the actin cytoskeleton, regulates formation of membrane ruffles, cell adhesion and cell migration and plays a role in lipoprotein clearance (PMID: 29734839; 29679908; 28202039) Specification Tested Reactivity: rat Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg3416 Product name: Recombinant Rat M-CSF protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 33-508 aa of Sequence: EVSEHCSHMIGNGHLQILQQLIDSQMETACLIEYKFVDQEQLDDPVCYLKKAFVLVQVIIEETMRFKDNTPNANATERLQELSMKLNSCFIKDYKEQNEACVQTYKESPLRLLEKIKNFFNETKNFLEKDWNIFSKNCNDSFAKCSSRDVVTKPDCNCLYPKATPSSDLASASPHQPPAPSMAPLADLAWDDSQRTEGSSLLPSDLPLRIEDPGSAKQRPPRSTCQTLESTEQPNHEDPQPHPSAGAPIPGVEDIIESSMGTNWVLEEASGEASEGFLTQERKFSPSNPVGGSIQAETDRPWARSASSPFPKLTEDQQPTNITDTPLTEVNPMRPTGQTLNNTPEKTDGSSTLREDQQEPRSPHFATLNPQRVGNSATPYAKLLPPKSHSWGIVLPLGELEGKKSTRDRRSPAELKGGPASEGAARPVAQSTRDRRSPAELKGGPASEGAARPVARFNSIPLTDTGSSIQDPQTSA Predict reactive species Full Name: colony stimulating factor 1 (macrophage) Calculated Molecular Weight: 62 kDa Gene Symbol: Csf1 Gene ID (NCBI): 78965 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q8JZQ0 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.