Proteintech, 98701-3-RR, Anti-Canine IL-2 Rabbit Recombinant Antibody

Size: 100ug The IL-2 (98701-3-RR) by Proteintech is a Recombinant antibody targeting IL-2 in FC (Intra) applications with reactivity to canine samples 98701-3-RR targets IL-2 in FC (Intra) applications and shows reactivity with canine samples. Tested Applications Positive FC (Intra) detected in: Transfected CHO-K1 cells Recommended dilution Flow Cytometry (FC) (INTRA): FC (INTRA) : 0.25 ug per 10^6 cells in a 100 µl suspension Background Information Interleukin-2 (IL-2) is a four-helix bundle, type I cytokine that functions as a growth factor for a wide range of leukocytes. In the immune system, IL-2 is essential for immune homeostasis, normal T regulatory cell function, and self-tolerance. It regulates immune cell homeostasis and has been used to treat a range of disorders including cancer and autoimmune disease. IL-2 signals through heterodimerization of the IL-2Rβ and IL-2Rγ receptor subunits (PMID: 25992858, 24907378, 15034008, 17981641). Specification Tested Reactivity: canine Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg4556 Product name: Recombinant Canine IL-2 protein (rFc Tag) (HPLC verified) Source: mammalian cells -derived, pHZ-KIsec-N-rFc Tag: N-rFc Domain: 21-155 aa of NM_001003305.1 Sequence: APITSSSTKETEQQMEQLLLDLQLLLNGVNNYENPQLSRMLTFKFYTPKKATEFTHLQCLAEELKNLEEVLGLPQSKNVHLTDTKELISNMNVTLLKLKGSETSYNCEYDDETATITEFLNKWITFCQSIFSTLT Predict reactive species Full Name: IL-2 Calculated Molecular Weight: 18 kDa GenBank Accession Number: NM_001003305.1 Gene Symbol: IL-2 Gene ID (NCBI): 403989 Conjugate: Unconjugated Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q29416 Storage Buffer: PBS with 0.09% sodium azide, pH 7.3. Storage Conditions: Store at 2 - 8°C. Stable for one year after shipment.