Proteintech, APC-FcA98101, FcZero-rAb™ APC Anti-Human SIRP Alpha/CD172a Rabbit Recombinant Antibody

Size: 100tests The SIRP Alpha/CD172a (APC-FcA98101) by Proteintech is a Recombinant antibody targeting SIRP Alpha/CD172a in FC applications with reactivity to human samples APC-FcA98101 targets SIRP Alpha/CD172a in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: human peripheral blood leukocytes Recommended dilution Flow Cytometry (FC): FC : 5 ul per 10^6 cells in 100 μl suspension Background Information SIRP Alpha, also known as CD172a, SHPS-1, and BIT, belongs to the SIRP family. SIRP Alpha is a transmembrane glycoprotein expressed explicitly on myeloid cells and provides a "do not eat me" signal after engaging with integrin-associated protein CD47 on tumor cells (PMID: 36419386). SIRP Alpha shows heterogeneity in molecular weight (~65-120 kDa) in various tissues due to differential glycosylation (PMID: 18051954). Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant protein Predict reactive species Full Name: signal-regulatory protein alpha Calculated Molecular Weight: 55 kDa GenBank Accession Number: NM_080792 Gene Symbol: SIRP Alpha Gene ID (NCBI): 140885 Conjugate: APC Fluorescent Dye Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm Form: Liquid Purification Method: Protein A purification UNIPROT ID: P78324 Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.