Proteintech, APC-FcA98112, FcZero-rAb™ APC Anti-Human TNFRSF9/CD137 Rabbit Recombinant Antibody

Size: 100tests The TNFRSF9/CD137 (APC-FcA98112) by Proteintech is a Recombinant antibody targeting TNFRSF9/CD137 in FC applications with reactivity to human samples APC-FcA98112 targets TNFRSF9/CD137 in FC applications and shows reactivity with human samples. Tested Applications Positive FC detected in: Con-A treated human PBMCs Recommended dilution Flow Cytometry (FC): FC : 5 ul per 10^6 cells in a 100 µl suspension Background Information CD137, also known as TNFRSF9 or 4-1BB, is an inducible T cell surface receptor that belongs to the tumor necrosis factor receptor superfamily. CD137 is a transmembrane protein expressed on the surface of activated T-cells. In addition, activation-dependent expression of CD137 has also been found in B lymphocytes, monocytes, and diverse nonlymphoid cell types. CD137 provides a co-stimulatory signal that enhances the survival, and differentiation of cells, and has a crucial role in the development of CD8 cytotoxic T cells and anti-tumor immunity. (PMID: 9826581; 23696891) Specification Tested Reactivity: human Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: Recombinant Protein Predict reactive species Full Name: tumor necrosis factor receptor superfamily, member 9 Calculated Molecular Weight: 28 kDa GenBank Accession Number: BC006196 Gene Symbol: TNFRSF9/CD137 Gene ID (NCBI): 3604 Conjugate: APC Fluorescent Dye Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q07011 Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.