Proteintech, APC-FcA98341, FcZero-rAb™ APC Anti-Mouse ICOS/CD278 Rabbit Recombinant Antibody

Size: 100ug The ICOS/CD278 (APC-FcA98341) by Proteintech is a Recombinant antibody targeting ICOS/CD278 in FC applications with reactivity to mouse samples APC-FcA98341 targets ICOS/CD278 in FC applications and shows reactivity with mouse samples. Tested Applications Positive FC detected in: anti-CD3/CD28 treated BALB/c spleen cells Recommended dilution Flow Cytometry (FC): FC : 0.1 ug per 10^6 cells in a 100 µl suspension Background Information Inducible T cell co-stimulator (ICOS) is related to the CD28 superfamily and is highly expressed on activated T cells as well as regulatory T cells and is crucial for the survival and function of T cells, Th2 cell differentiation, and lung inflammatory responses. Binding ICOS to ICOS-ligand (ICOS-L) activates a cascade of intracellular signaling molecules that prevent apoptosis and lead to the production of cytokines such as IL-4 and IL-13. Specification Tested Reactivity: mouse Host / Isotype: Rabbit / IgG Class: Recombinant Type: Antibody Immunogen: CatNo: Eg3198 Product name: Recombinant Mouse ICOS/CD278 protein (rFc Tag) Source: mammalian cells -derived, pHZ-KIsec-C-rFc Tag: C-rFc Domain: 21-144 aa of NM_017480.2 Sequence: EINGSADHRMFSFHNGGVQISCKYPETVQQLKMRLFREREVLCELTKTKGSGNAVSIKNPMLCLYHLSNNSVSFFLNNPDSSQGSYYFCSLSIFDPPPFQERNLSGGYLHIYESQLCCQLKLWL Predict reactive species Full Name: inducible T-cell co-stimulator Calculated Molecular Weight: 23kDa GenBank Accession Number: NM_017480.2 Gene Symbol: Icos Gene ID (NCBI): 54167 Conjugate: APC Fluorescent Dye Excitation/Emission Maxima Wavelengths: 650 nm / 660 nm Form: Liquid Purification Method: Protein A purification UNIPROT ID: Q9WVS0 Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.