Proteintech, CL488-65141, CoraLite® Plus 488 Anti-Mouse CD4 (RM4-5)

Size: 100ug The CD4 (CL488-65141) by Proteintech is a Monoclonal antibody targeting CD4 in IF/ICC, FC applications with reactivity to Mouse samples CL488-65141 targets CD4 in IF/ICC, FC applications and shows reactivity with Mouse samples. Tested Applications Positive IF/ICC detected in: mouse splenocytes Positive FC detected in: mouse splenocytes Recommended dilution Immunofluorescence (IF)/ICC: IF/ICC : 1:250-1:1000 Flow Cytometry (FC): FC : 0.25 ug per 10^6 cells in 100 μl suspension Background Information CD4 is a 55-kDa transmembrane glycoprotein expressed on T helper cells, majority of thymocytes, monocytes, macrophages, and dendritic cells (PMID: 9304802; 12213222). CD4 is an accessory protein for MHC class-II antigen/T-cell receptor interaction. It plays an important role in T helper cell development and activation (PMID: 9539765; 3112582). CD4 serves as a receptor for the human immunodeficiency virus (HIV) (PMID: 9304802). Specification Tested Reactivity: Mouse Cited Reactivity: mouse Host / Isotype: Rat / IgG2a, kappa Class: Monoclonal Type: Antibody Immunogen: BALB/c mouse thymocytes Predict reactive species Full Name: CD4 antigen GenBank Accession Number: BC039137 Gene Symbol: Cd4 Gene ID (NCBI): 12504 RRID: AB_2883201 Conjugate: CoraLite® Plus 488 Fluorescent Dye Excitation/Emission Maxima Wavelengths: 493 nm / 522 nm Form: Liquid Purification Method: Affinity purification UNIPROT ID: P06332 Storage Buffer: PBS with 0.09% sodium azide and 0.5% BSA, pH 7.3. Storage Conditions: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.