Product Description
Size: 10ug
The TCF7 (G14464-1-5C) by Proteintech is a Polyclonal antibody targeting TCF7 in Single Cell (Intra) applications with reactivity to Human samples
G14464-1-5C targets TCF7 in Single Cell (Intra) applications and shows reactivity with Human samples.
Tested Applications
Positive Single Cell (Intra) detected in: 10x Genomics Gene Expression Flex with Feature Barcodes and Multiplexing product.
Recommended dilution
SINGLE CELL (INTRA): <0.5ug/test
Background Information
TCF7, also known as TCF1, belongs to the TCF/LEF family. TCF7 is part of the Wnt signaling pathway and plays an important role in the differentiation and self-renewal of memory T cells. It has been found that TCF7 is necessary to revive T cells in response to PD-1 blockade against viral infection or cancer. TCF7 is mainly expressed in T-cells and is also detected in proliferating intestinal epithelial cells and in the basal epithelial cells of mammary gland epithelium. TCF7 has 16 isoforms with the molecular mass of 28-54 kDa (PMID: 34044317).
Specification
Tested Reactivity: Human
Host / Isotype: Rabbit / IgG
Class: Oligo Conjugate
Type: Polyclonal
Immunogen: CatNo: Ag5792 Product name: Recombinant human TCF7 protein Source: e coli. -derived, PGEX-4T Tag: GST Domain: 1-384 aa of BC048769 Sequence: MPQLDSGGGGAGGGDDLGAPDELLAFQDEGEEQDDKSRDSAAGPERDLAELKSSLVNESEGAAGGAGIPGVPGAGAGARGEAEALGREHAAQRLFPDKLPEPLEDGLKAPECTSGMYKETVYSAFNLLMHYPPPSGAGQHPQPQPPLHKANQPPHGVPQLSLYEHFNSPHPTPAPADISQKQVHRPLQTPDLSGFYSLTSGSMGQLPHTVSWFTHPSLMLGSGVPGHPAAIPHPAIVPPSGKQELQPFDRNLKTQAESKAEKEAKKPTIKKPLNAFMLYMKEMRAKVIAECTLKESAAINQILGRRWHALSREEQAKYYELARKERQLHMQLYPGWSARDNYGKKKRRSREKHQESTTGGKRNAFGTYPEKAAAPAPFLPMTVL Predict reactive species
Full Name: MultiPro® 5CFLX Anti-Human TCF7 (Polyclonal)
Calculated Molecular Weight: 42 kDa
GenBank Accession Number: BC048769
Gene Symbol: TCF1/TCF7
Gene ID (NCBI): 6932
ENSEMBL Gene ID: ENSG00000081059
RRID: AB_3673888
Conjugate: 5CFLX
Full Oligo Sequence: CGGAGATGTGTATAAGAGACAGCGCCTATAGAGACGCCCCATATAAGAAA
Barcode Sequence: CGCCTATAGAGACGC
Form: Liquid
UNIPROT ID: P36402
Storage Buffer: PBS with 1mM EDTA and 0.09% sodium azide , pH 7.3.
Storage Conditions: 2-8°C Stable for one year after shipment.
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Collaboration
Tony Tang
Email: Tony.Tang@iright.com
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