Proteintech, KE10020, Mouse IL-17A ELISA Kit

Size: 96t / 5*96t / 10*96t Background Information Il17a, also named as Il-17, is a proinflammatory cytokine. Il-17, synthesized only by memory T cells and natural killer cells, has pleiotropic effects, mainly in the recruitment and activation of neutrophils. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. The Il-17 receptor is a type I transmembrane protein, that is widely expressed on epithelial cells, fibroblasts, B and T cells, and monocytic cells. In psoriatic skin lesions, both Th17 cells and their downstream effector molecules, e.g. Il-17 and IL-22, are highly increased. Specification Product name: Mouse IL-17A ELISA Kit Tests: 1 X 96 well plate Sample type: Serum, Plasma, Cell culture supernatants, Tissue lysates Assay type: Sandwich Sensitivity: 2.6 pg/mL Range: 7.8-500 pg/mL Reactivity: Mouse Tested applications: Sandwich ELISA Gene ID (NCBI): 16171 Mouse serum: 93% Cell culture supernatants: 93% 1: 20 2: 20 3: 20 1: 24 2: 24 3: 24 Storage Instructions: All the reagents are stored at 2-8℃ for 6 months or -20℃ for 12 months. Refer to the protocol for further storage instructions. Synonyms: Ctla 8, Ctla8, CTLA-8, Il17, IL-17, Il17a, IL-17A, interleukin 17A, Interleukin-17A