Thermo Fisher, 27-1424-04, 8-oxo-dG Phosphoramidite, standard grade, serum vial bottle

Thermo Fisher, 27-1424-04, 8-oxo-dG Phosphoramidite, standard grade, serum vial bottle 8-oxo-dG CEP is a phosphoramidite containing an oxidized deoxyguanosine (dG), and it facilitates the investigation of the structure and activity when incorporated into an oligonucleotide. In nature, 8-oxo-dG DNA lesions are formed with reactive oxygen species (ROS), and is removed by by the base excision repair (BER) mechanism. This modification is significant in mutagenesis, carcinogenesis, and has been proven useful as a biomarker. This product is supplied in a 5 mL amber bottle with a serum vial neck style, which is compatible with most Applied Biosystems synthesizers and AKTA synthesizers of oligonucleotide synthesizers.
Features:
• Full chemical name—5'-O-(4,4'-Dimethoxytrityl)‐N2-isobutyryl-8-oxo-deoxyguanosine-3'-O-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite
• Molecular formula—C44H54N7O9P
• Base—8-oxo-dG
• Base Protection—iBu
• Formula weight—855.
9 g/mol
• CAS number—143060-53-1
• HPLC Purity—≥98.
0%
•31P NMR Purity—≥98.
0%For Use With (Equipment): AKTA Synthesizers, Applied Biosystems Synthesizers
Form: Powder
Grade: Standard
Nucleic Acid Type: DNA
Nucleoside Type: Deoxyguanosine (dG)
Product Type: 8-oxo-dG CEP
Purity: 98%
Quantity: 0.
25 g
Reagent Type: Phosphoramidite
Shipping Condition: Room Temperature
Unit Size: Each