Waters, 176004592, BioResolve SEC mAb Column, 200Å, 2.5 µm, 4.6 x 150 mm, 1/pk with mAb Size Variant Standard

The BioResolve SEC mAb 4.6 x 150 mm Column contains 2.5 µm BEH particle technology and is application specifically tested with the mAb Size Variant Standard to ensure accurate and highly reproducible quantitation of monoclonal antibody (mAb) monomers from frequently associated high molecular weight aggregates (≥300,000 Da) and lower molecular weight fragments (e.g., ≤100,000 Da).  This column is also available with Water mAb Size Variant Standard (PN 186009429) at no extra charge.

Specifications
Chemistry: SEC
Separation Mode: SEC
Particle Substrate: Hybrid
pH Range Min: 2.5 pH
pH Range Max: 8 pH
Temperature Limits: 60 C
Maximum Pressure: 4500 psi (310 Bar)
Endcapped: No
Bonding Technology: Diol (OH)
Silanol Activity: Low
Molecular Weight Range Min: 10000
Molecular Weight Range Max: 450000
Particle Shape: Spherical
Particle Size: 2.5 µm
Endfitting Type: Parker-style
Pore Size: 200 Å
QC Tested: Protein
Format: Online Column
Packing Solvent: 10% acetonitrile/90% 25 mM sodium phosphate pH 7.0 + 100 mM KCl
Surface Area: 220
System: HPLC
Particle Technology: BEH
Technique: LC
USP Classification: L33
Inner Diameter: 4.6 mm
Length: 150 mm
Carbon Load: 12 %
eCord: Yes
UNSPSC: 41115711
Application: Protein
Brand: BioResolve
Product Type: Columns
Units per Package: 1 pk

Additional Information
BioResolve SEC mAb Column, 200Å, 2.5 µm, 4.6 x 150 mm, 1/pk with mAb Size Variant Standard Don’t just change the way you quantitate monoclonal antibodies, transform them for the better with the help of the BioResolve SEC mAb Column. This column is specifically designed for the accurate, reproducible quantitation of monoclonal antibody monomers from both high and lower molecular weight fragments. But to ensure you only receive the most accurate and best-performing column time and again, each BioResolve SEC mAb Column is QC tested with the Waters Size Variant Standard. We’ve included this QC reference material free of charge with your column so you can benchmark your own LC-MS systems properly. Upgrade your mAb separations with the BioResolve SEC mAb Column now. A major concern when hard at work in the lab on monoclonal antibody quantitation is column contamination. Although proper sample preparation processes should be followed to ensure you only have the cleanest samples running through your analytical column, there’s always a chance that very small contaminants in the mobile phase stream can enter and foul your column over time. To increase overall column lifetimes and prevent that contamination, we’re happy to provide the BioResolve SEC mAb Guard . This guard column seamlessly incorporates into your existing workflow to provide enhanced protection against contaminants. Plus, when the guard has become worn and needs to be replaced, you can do so with another genuine replacement from Waters. At the heart of the BioResolve SEC mAb Column is Ethylene-Bridged Hybrid (BEH) particle technology. Thanks to the intrinsic chemical stability of the BEH particle, you can develop methods with a wide pH range with no concerns about performance. And because we care deeply about performance, this column can be used on UHPLC, HPLC and UPLC systems. This especially comes in handy when developing methods. Stock up your lab today with all of the incredible instruments, products and resources from Waters, and you’ll be well on your way to changing your experiments for the better. We have everything from quality control reference materials to lab informatics, making us a one-stop shop for all your LC-MS needs. Shop lab equipment today.

FAQ
What’s the BioResolve SEC mAb Column’s Molecular Weight Range? The BioResolve SEC mAb Column offers a molecular weight range of 10,000 to 450,000.