Waters, 186005302, ACQUITY UPLC CSH C18 Column, 130Å, 1.7 µm, 3 mm X 150 mm, 1/pk

ACQUITY CSH C18 columns were designed to provide alternate selectivity compared to other reversed-phase UPLC columns. These ultra-efficient columns overcome peak shape asymmetry and poor loading capacity for basic compounds, column bleed, and rapid mobile-phase re-equilibration.

Specifications
Chemistry: C18
Separation Mode: Reversed Phase
Particle Substrate: Hybrid
pH Range Min: 1 pH
pH Range Max: 11 pH
Maximum Pressure: 18000 psi (1240 Bar)
Endcapped: Yes
Silanol Activity: Low
Particle Shape: Spherical
Particle Size: 1.7 µm
Endfitting Type: Parker-style
Pore Size: 130 Å
Format: Column
Surface Area: 185
System: UPLC, UHPLC
Particle Technology: CSH
USP Classification: L1
Inner Diameter: 3 mm
Length: 150 mm
Carbon Load: 15 %
eCord: Yes
UNSPSC: 41115709
Brand: ACQUITY UPLC
Product Type: Columns
Units per Package: 1 pk

Additional Information
ACQUITY UPLC CSH C18 Column, 130Å, 1.7 µm, 3 mm X 150 mm, 1/pk Waters created the ACQUITY UPLC CSH C18 Column in response to feedback gathered at numerous customer forums. When compared to other reversed-phase UPLC columns, the lab equipment was created to offer a different level of selectivity. These incredibly effective columns overcome column bleed, quick mobile-phase re-equilibration, peak shape asymmetry, and limited loading capacity for basic chemicals. The Charged Surface Hybrid (CSH) Technology, which is the next step in particle technology, is the main driving force behind the ACQUITY UPLC CSH columns. The Charged Surface Hybrid (CSH) Technology, which is the primary working principle of the ACQUITY UPLC CSH columns, was created by Waters. Since the ACQUITY UPLC CSH C18 Column uses CSH Technology, which provides Trifluoroacetic Acid (TFA) peak shape performance without the use of TFA, method development is quicker and simpler. Trifluoroacetic acid can provide crisp peak forms for basic chemicals, but it is a difficult ion-pairing agent to get rid of from the ACQUITY phase of a liquid chromatography column once it has been exposed to it. In contrast, the ACQUITY UPLC CSH C18 Column can produce better peak shape performance when using mobile phase additives that are favorable to MS, like formic acid. This also results in the faster and more straightforward method development as formic acid does not show the effects of an ion-pairing agent. Additionally, the lab equipment provides increased analytical loadability, delivering sharper, narrower peaks for basic compounds under the acidic, low ionic strength mobile phase conditions. The columns are also ideally suited for isolation and purification as the increased loadability allows for the use ofa narrower preparative column, reducing solvent consumption and fraction volumes. In contrast to the two ACQUITY brands from Waters, the ACQUITY UPLC BEH and XBridge, the ACQUITY UPLC CSH C18 Column offers alternative selectivity, a larger range, and a unique design. The ACQUITY UPLC CSH C18 Column offers a wide range of selectivities without sacrificing essential performance characteristics like peak shape for basic chemicals, minimum column bleed, and seamless transferability between various particle sizes and column formats. Learn more about the Reversed-Phase QC Reference Material .

FAQ
Does The ACQUITY UPLC CSH C18 Column Offer A Broad pH Range? The Waters ACQUITY UPLC CSH C18 Column listed here is able to conduct analysis within the 1-11 pH range. What Is The Recommended Maximum Pressure For The ACQUITY UPLC CSH C18 Column? The maximum pressure that is used for the ACQUITY UPLC CSH C18 Column should not exceed 18,000 psi (1240 Bar).