Waters, 186009836, XBridge Premier Oligonucleotide BEH C18 Column, 130Å, 2.5 µm, 2.1 x 50 mm

XBridge Premier Oligonucleotide Columns are used to separate detritylated synthetic oligonucleotides based on ion-pair, reversed-phase chromatography. Each column is QC tested using Waters MassPrep OST standards to ensure repeatable performance for your most demanding oligonucleotide assays. This column is part of the MaxPeak Premier Class of Columns, which deliver the chromatographic performance expected from our particle technologies while increasing reproducibility, peak shape, and recovery for metal-sensitive analytes.

Specifications
Chemistry: C18
Separation Mode: Reversed Phase
Particle Substrate: Hybrid
pH Range Min: 1 pH
pH Range Max: 12 pH
Maximum Pressure: 18000 psi (1240 Bar)
Endcapped: Yes
Silanol Activity: Low
Particle Shape: Spherical
Particle Size: 2.5 µm
Endfitting Type: Parker-style
Pore Size: 130 Å
Format: Premier Column
Surface Area: 185
System: UPLC, UHPLC
Particle Technology: BEH
Technique: LC
USP Classification: L1
Inner Diameter: 2.1 mm
Length: 50 mm
Carbon Load: 18 %
eCord: Yes
UNSPSC: 41115709
Application: Oligonucleotide, Gene Therapeutics
Brand: XBridge
Product Type: Columns
Units per Package: 1 pk

Additional Information
XBridge Premier Oligonucleotide BEH C18 Column, 130Å, 2.5 µm, 2.1 x 50 mm Oligonucleotide separation technology designed for the future is here with the XBridge Premier Oligonucleotide BEH C18 Column. This UHPLC column incorporates Ethylene Bridged Hybrid (BEH) particles and MaxPeak High Performance Surface technology to provide an all-in-one solution for oligo separations. What’s more, you can equip this column with VanGuard FIT technology to extend its lifetime across all your UHPLC assays. This way you can maximize efficiency in the lab and in turn increase business profitability. Detritylated synthetic oligonucleotides present a series of challenges when being the chosen sample for UHPLC separations. That’s why you want a superior BEH C18 column in your toolkit for all related assays. Luckily for you, the XBridge Premier Oligonucleotide BEH C18 Column is uniquely suited to work under ion-pair, reversed-phase chromatography conditions, resulting in reliable performance time and again. The XBridge Premier Oligonucleotide BEH C18 Column isn’t just suited for oligo separations either, as it offers premium performance for a broad range of compounds. Plus, all XBridge Premier columns provide the highest pH stability in a UHPLC column. Add these facets together and it’s easy to see why liquid chromatography labs across the globe trust Waters products to help pave the path to MS adoption. UHPLC column protection is just as important as performance. That’s why you can couple your XBridge Premier Oligonucleotide BEH C18 Column with a VanGuard FIT Cartridge to enjoy a longer column lifetime and less risk of losses in signal intensity. What’s more, VanGuard FIT Technology can prevent your UHPLC column from suffering chemical fouling. To further protect oligonucleotide separations from losses in signal intensity, the XBridge Premier Column line incorporates MaxPeak High Performance Surface technology. MaxPeak increases reproducibility and peak shape while reducing surface-analyte interactions that might negatively affect your data. That kind of confidence is important to have when performing oligo separations. Protect your oligonucleotide-related UHPLC separations even further and stock your lab with all the necessary equipment when you shop with Waters. Shop for lab equipment now to check off your lab’s shopping list, or speak to your lab manager today about using Waters Corporation products.

FAQ
What is a BEH C18 Column? A BEH C18 column is a column used for general purpose, reversed-phase chromatography and offers extreme pH stability.