Abcam, ab118565, Anti-OCIAD2 antibody

Size: 50µg
Rabbit Polyclonal OCIAD2 antibody. Suitable for WB, IHC-P and reacts with Human samples. Cited in 3 publications. Immunogen corresponding to Synthetic Peptide within Human OCIAD2 conjugated to Keyhole Limpet Haemocyanin.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, WBSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Synthetic Peptide within Human OCIAD2 conjugated to Keyhole Limpet Haemocyanin. The exact immunogen used to generate this antibody is proprietary information.Q56VL3

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Protein A, Storage buffer-pH: 7.4Preservative: 0.02% Sodium azideConstituents: PBS, Shipped at conditions-Blue Ice, Appropriate short-term storage duration-1-2 weeks, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
OCIAD2 also known as ovarian cancer immunoreactive antigen domain containing 2 is a protein found in humans. It has a molecular mass of approximately 29 kDa. OCIAD2 is expressed in various tissues including the ovary breast and kidney. It localizes mainly in the cytoplasm and mitochondria suggesting a role in cellular processes related to these organelles.
Biological function summary
OCIAD2 impacts cellular processes through its involvement in cell differentiation and cellular stress responses. It may associate with multiprotein complexes that regulate these functions. Studies indicate OCIAD2 interacts with mitochondrial outer membrane components which hints it might play a role in mitochondrial dynamics. Through these interactions OCIAD2 contributes to maintaining cellular homeostasis during stress.
Pathways
OCIAD2 participates in pathways like oxidative phosphorylation and apoptosis. These pathways are important for cellular energy production and programmed cell death. OCIAD2 may interact with proteins such as cytochrome c and members of the Bcl-2 family in these processes. Through its involvement OCIAD2 helps regulate energy balance and cell survival influencing the fate of cells under various stimuli.
OCIAD2 has a connection to ovarian cancer and breast cancer. Abnormal expression of OCIAD2 associates with tumor progression and poor prognosis in ovarian cancer. In this context OCIAD2 might work with proteins like BRCA1 and HER2 which are critical in cancer biology. Understanding OCIAD2's role in these cancers could lead to potential therapeutic strategies or biomarkers for diagnosis.