Abcam, ab120035, MTEP hydrochloride, mGlu5 antagonist

Size: 10mg / 50mg
MW 236.72 Da, Purity >99%. Brain penetrant, potent, selective and non-competitive mGlu5 receptor antagonist (IC50 = 5 nM in Ca2+-flux assay; Ki = 16 nM). In vivo anxiolytic, devoid of side effects seen with MPEP and benzodiazepines. Soluble in 1 ml water to give specified mM/ml concentration.
Key facts
CAS number:1186195-60-7,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:236.72 Da,
Molecular formula:C11H9ClN2S,
PubChem:45073467,
Nature:Synthetic,
Biochemical name:MTEP hydrochloride,
Biological description:Brain penetrant, potent, selective and non-competitive mGlu5 receptor antagonist (IC50 = 5 nM in Ca2+-flux assay; Ki = 16 nM). In vivo anxiolytic, devoid of side effects seen with MPEP and benzodiazepines. Soluble in 1 ml water to give specified mM/ml concentration.,
Canonical smiles:CC1=NC(=CS1)C#CC2=CN=CC=C2.Cl,
InChi:InChI=1S/C11H8N2S.ClH/c1-9-13-11(8-14-9)5-4-10-3-2-6-12-7-10;/h2-3,6-8H,1H3;1H,
InChiKey:YCIOJDKGCWAHLR-UHFFFAOYSA-N,
IUPAC Name:2-methyl-4-(2-pyridin-3-ylethynyl)-1,3-thiazole;hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months