Abcam, ab120201, LY 456236, mGlu1 non competitive antagonist

Size: 10mg / 50mg
MW 317.77 Da, Purity >99%. Selective non-competitive antagonist at the mGlu1 receptor. Inhibits agonist induced phosphoinositide hydrolysis *in vitro* (IC50 = 140 nM) and *in vivo* following systemic administration.
Key facts
CAS number:338738-57-1,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:317.77 Da,
Molecular formula:C16H16ClN3O2,
PubChem:9926998,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mM (with warming),
Biochemical name:LY 456236 Hydrochloride,
Biological description:Selective non-competitive antagonist at the mGlu1 receptor. Inhibits agonist induced phosphoinositide hydrolysis *in vitro* (IC50 = 140 nM) and *in vivo* following systemic administration.,
Canonical smiles:COC1=CC=C(C=C1)NC2=NC=NC3=C2C=C(C=C3)OC.Cl,
InChi:InChI=1S/C16H15N3O2.ClH/c1-20-12-5-3-11(4-6-12)19-16-14-9-13(21-2)7-8-15(14)17-10-18-16;/h3-10H,1-2H3,(H,17,18,19);1H,
InChiKey:AVKFOWUSTVWZQN-UHFFFAOYSA-N,
IUPAC Name:6-methoxy-N-(4-methoxyphenyl)quinazolin-4-amine;hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months