Product Description
Size: 10mg / 50mg
MW 338.2 Da, Purity >98%. Positive allosteric selective modulator at mGluR4 (EC50 values are 798 and 693 nM at human and rat mGluR4 receptors, respectively). It has advantages over PHCCC (ab120043) as it is water soluble and more potent. Shows limited blood-brain barrier permeability. Active in behavioural models of Parkinson's disease following icv injection. Also available in simple stock solutions (ab146686) - add 1 ml of water to get an exact, ready-to-use concentration.
Key facts
CAS number:1259372-69-4,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:338.2 Da,
Molecular formula:C14H14Cl2NNaO3,
PubChem:52974247,
Nature:Synthetic,
Solubility:Soluble in water to 100 mM,
Biochemical name:VU0155041 sodium salt,
Biological description:Positive allosteric selective modulator at mGluR4 (EC50 values are 798 and 693 nM at human and rat mGluR4 receptors, respectively). It has advantages over PHCCC (ab120043) as it is water soluble and more potent. Shows limited blood-brain barrier permeability. Active in behavioural models of Parkinson's disease following icv injection. Also available in simple stock solutions (ab146686) - add 1 ml of water to get an exact, ready-to-use concentration.,
Canonical smiles:C1CCC(C(C1)C(=O)NC2=CC(=CC(=C2)Cl)Cl)C(=O)[O-].[Na+],
InChi:InChI=1S/C14H15Cl2NO3.Na/c15-8-5-9(16)7-10(6-8)17-13(18)11-3-1-2-4-12(11)14(19)20;/h5-7,11-12H,1-4H2,(H,17,18)(H,19,20);/q;+1/p-1,
InChiKey:ZFDOLOCYGVTGDQ-UHFFFAOYSA-M,
IUPAC Name:sodium;2-[(3,5-dichlorophenyl)carbamoyl]cyclohexane-1-carboxylate
Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months
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Collaboration
Tony Tang
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