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BRAND / VENDOR: Abcam

Abcam, ab120409, RuBi-GABA, caged-GABA compound

CATALOG NUMBER: ab120409
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Product Description

Size: 10mg
MW 922.8 Da. Novel caged-GABA compound that uses a ruthenium complex as photosensor. Can be excited with visible wavelengths, providing greater tissue penetration, less photo-toxicity, and faster photorelease kinetics than other UV light-sensitive caged compounds. Can be used for GABA receptor mapping, and optical silencing of neuronal firing.
Key facts
CAS number:1028141-88-9,
Form:SolidSee storage information,
Molecular weight:922.8 Da,
Molecular formula:C42H39F6N5O2P2Ru,
PubChem:129316180,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mMFor water solubility, please refer to Guideline for Use Information Sheet,
Biochemical name:RuBi-GABA,
Biological description:Novel caged-GABA compound that uses a ruthenium complex as photosensor. Can be excited with visible wavelengths, providing greater tissue penetration, less photo-toxicity, and faster photorelease kinetics than other UV light-sensitive caged compounds. Can be used for GABA receptor mapping, and optical silencing of neuronal firing.,
Canonical smiles:C1=CC=C(C=C1)P(C2=CC=CC=C2)C3=CC=CC=C3.C1=CC=NC(=C1)C2=CC=CC=N2.C1=CC=NC(=C1)C2=CC=CC=N2.C(CC(=O)[O-])CN.F[P-](F)(F)(F)(F)F.[Ru+2],
InChi:InChI=1S/C18H15P.2C10H8N2.C4H9NO2.F6P.Ru/c1-4-10-16(11-5-1)19(17-12-6-2-7-13-17)18-14-8-3-9-15-18;2*1-3-7-11-9(5-1)10-6-2-4-8-12-10;5-3-1-2-4(6)7;1-7(2,3,4,5)6;/h1-15H;2*1-8H;1-3,5H2,(H,6,7);;/q;;;;-1;+2/p-1,
InChiKey:SWFWLLYVSYURHZ-UHFFFAOYSA-M,
IUPAC Name:4-aminobutanoate;2-pyridin-2-ylpyridine;ruthenium(2+);triphenylphosphane;hexafluorophosphate

Product details:
RuBi-GABA is light sensitive and it is recommended that the compound is protected from light.
Sold under license from Columbia University; Patent Pending.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions


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Collaboration

Tony Tang

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