Abcam, ab120420, Buspirone hydrochloride, 5-HT1A agonist

Size: 1g / 5g
MW 422 Da, Purity >99%. 5-HT1A partial agonist (Ki = 9.3 - 29.5 nM). Anxiolytic *in vivo*. Many reported effects including actions on dopaminergic and noradrenergic pathways, as well as the GABA-benzodiazepine receptor chloride ionophore complex.
Key facts
CAS number:33386-08-2,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:422 Da,
Molecular formula:C21H32ClN5O2,
PubChem:36431,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:Buspirone hydrochloride,
Biological description:5-HT1A partial agonist (Ki = 9.3 - 29.5 nM). Anxiolytic *in vivo*. Many reported effects including actions on dopaminergic and noradrenergic pathways, as well as the GABA-benzodiazepine receptor chloride ionophore complex.,
Canonical smiles:C1CCC2(C1)CC(=O)N(C(=O)C2)CCCCN3CCN(CC3)C4=NC=CC=N4.Cl,
InChi:InChI=1S/C21H31N5O2.ClH/c27-18-16-21(6-1-2-7-21)17-19(28)26(18)11-4-3-10-24-12-14-25(15-13-24)20-22-8-5-9-23-20;/h5,8-9H,1-4,6-7,10-17H2;1H,
InChiKey:RICLFGYGYQXUFH-UHFFFAOYSA-N,
IUPAC Name:8-[4-(4-pyrimidin-2-ylpiperazin-1-yl)butyl]-8-azaspiro[4.5]decane-7,9-dione;hydrochloride

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months