Abcam, ab120502, GW542573X, KCa2 channel activator

Size: 10mg / 50mg
MW 364.4 Da, Purity >99%. Novel activator of KCa2 ('SK') channels. Selective SK1 channel activator (EC50 = 8.2 μM). First true activator of KCa2.x and KCa3.1 channels; displays 100-fold greater selectivity for KCa2.x over KCa3.1.
Key facts
CAS number:660846-41-3,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:364.4 Da,
Molecular formula:C19H28N2O5,
PubChem:24885053,
Nature:Synthetic,
Solubility:Soluble in ethanol to 100 mM,
Biochemical name:Tert-butyl 4-({[(2-methoxyphenyl)carbamoyl]oxy}methyl)piperidine-1-carboxylate,
Biological description:Novel activator of KCa2 ('SK') channels. Selective SK1 channel activator (EC50 = 8.2 μM). First true activator of KCa2.x and KCa3.1 channels; displays 100-fold greater selectivity for KCa2.x over KCa3.1.,
Canonical smiles:CC(C)(C)OC(=O)N1CCC(CC1)COC(=O)NC2=CC=CC=C2OC,
InChi:InChI=1S/C19H28N2O5/c1-19(2,3)26-18(23)21-11-9-14(10-12-21)13-25-17(22)20-15-7-5-6-8-16(15)24-4/h5-8,14H,9-13H2,1-4H3,(H,20,22),
InChiKey:SAXGSDIZIYFNKD-UHFFFAOYSA-N,
IUPAC Name:tert-butyl 4-[(2-methoxyphenyl)carbamoyloxymethyl]piperidine-1-carboxylate

Product details:
Supplied in ethanol (25 mg/ml). Please note this compound is unstable as the solid form and unstable in DMSO

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions