Abcam, ab120638, SB 202190, cell-permeable p38 MAPK inhibitor

Size: 10mg / 50mg
MW 331.3 Da, Purity >99%. Highly selective, potent and cell-permeable p38 MAPK inhibitor (IC 50 values are 50 and 100 nM at SAPK2a/p38 and SAPK2b/p38β2, respectively). Selective over a wide range of other kinases. Apoptosis and autophagy inducer. 3D Growth matrix component and additive for long term growth; also component of gastric organoid culture media.
Key facts
CAS number:152121-30-7,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:331.3 Da,
Molecular formula:C20H14FN3O,
PubChem:5169,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:4-(4-Fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole,
Biological description:Highly selective, potent and cell-permeable p38 MAPK inhibitor (IC50 values are 50 and 100 nM at SAPK2a/p38 and SAPK2b/p38β2, respectively). Selective over a wide range of other kinases. Apoptosis and autophagy inducer. 3D Growth matrix component and additive for long term growth; also component of gastric organoid culture media.,
Canonical smiles:C1=CC(=CC=C1C2=NC(=C(N2)C3=CC=NC=C3)C4=CC=C(C=C4)F)O,
InChi:InChI=1S/C20H14FN3O/c21-16-5-1-13(2-6-16)18-19(14-9-11-22-12-10-14)24-20(23-18)15-3-7-17(25)8-4-15/h1-12,25H,(H,23,24),
InChiKey:QHKYPYXTTXKZST-UHFFFAOYSA-N,
IUPAC Name:4-[4-(4-fluorophenyl)-5-pyridin-4-yl-1H-imidazol-2-yl]phenol

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months