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BRAND / VENDOR: Abcam

Abcam, ab120652, Mevastatin, HMG-CoA reductase inhibitor

CATALOG NUMBER: ab120652
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Product Description

Size: 10mg / 50mg
MW 390.5 Da, Purity >98%. Potent HMG-CoA reductase inhibitor. Proapoptotic, able to arrest cells in G 1 by down-regulation of CDK4, CDK6 and cyclin D1 and up-regulation of p21 and p27.
Key facts
CAS number:73573-88-3,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:390.5 Da,
Molecular formula:C23H34O5,
PubChem:64715,
Nature:Synthetic,
Solubility:Soluble in ethanol to 10 mMSoluble in DMSO to 100 mM,
Biochemical name:Mevastatin,
Biological description:Potent HMG-CoA reductase inhibitor. Proapoptotic, able to arrest cells in G1 by down-regulation of CDK4, CDK6 and cyclin D1 and up-regulation of p21 and p27.,
Canonical smiles:CCC(C)C(=O)OC1CCC=C2C1C(C(C=C2)C)CCC3CC(CC(=O)O3)O,
Isomeric smiles:CC[C@H](C)C(=O)O[C@H]1CCC=C2[C@H]1[C@H]([C@H](C=C2)C)CC[C@@H]3C[C@H](CC(=O)O3)O,
InChi:InChI=1S/C23H34O5/c1-4-14(2)23(26)28-20-7-5-6-16-9-8-15(3)19(22(16)20)11-10-18-12-17(24)13-21(25)27-18/h6,8-9,14-15,17-20,22,24H,4-5,7,10-13H2,1-3H3/t14-,15-,17+,18+,19-,20-,22-/m0/s1,
InChiKey:AJLFOPYRIVGYMJ-INTXDZFKSA-N,
IUPAC Name:[(1S,7S,8S,8aR)-8-[2-[(2R,4R)-4-hydroxy-6-oxooxan-2-yl]ethyl]-7-methyl-1,2,3,7,8,8a-hexahydronaphthalen-1-yl] (2S)-2-methylbutanoate

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months


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