Abcam, ab120816, Itraconazole, Cytochrome p450 inhibitor

Size: 50mg / 100mg
MW 705.64 g/mol, Purity >99%. Cytochrome p450 CYP3A4 inhibitor (IC 50 = 16-26 nM for midazolam hydroxylation). Higher affinity for fungal enzymes over mammalian cytochrome p450. Limited ability to cross the blood-brain barrier. Antifungal activity.
Key facts
CAS number:84625-61-6,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:705.64 g/mol,
Molecular formula:C35H38Cl2N8O4,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mMSoluble in ethanol to 10 mM (with warming),
Biological description:Cytochrome p450 CYP3A4 inhibitor (IC50 = 16-26 nM for midazolam hydroxylation). Higher affinity for fungal enzymes over mammalian cytochrome p450. Limited ability to cross the blood-brain barrier. Antifungal activity.,
IUPAC Name:4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions