Abcam, ab120904, GANT 61, GLI1 and 2 inhibitor

Size: 10mg / 50mg
MW 429.61 g/mol, Purity >98%. Selective GLI1 and 2 inhibitor (IC 50 = 5 μM). Blocks the hedgehog/smoothened signaling pathway. Anticancer activity in vitro and in vivo .
Key facts
CAS number:500579-04-4,
Purity:>98%,
Molecular weight:429.61 g/mol,
Molecular formula:C27H35N5,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mMSoluble in ethanol to 100 mM,
Biological description:Selective GLI1 and 2 inhibitor (IC50 = 5 μM). Blocks the hedgehog/smoothened signaling pathway. Anticancer activity in vitro and in vivo.,
Canonical smiles:CN(C)C1=CC=CC=C1CN2CCCN(CC3=CC=CC=C3N(C)C)C2C4=CC=NC=C4,
IUPAC Name:2,2'-[[Dihydro-2-(4-pyridinyl)-1,3(2H,4H)-pyrimidinediyl]bis(methylene)]bis(N,N-dimethylbenzenamine)

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months