Abcam, ab120979, Ro 67-4853, Positive allosteric modulator of mGlu1

Size: 10mg / 50mg
MW 325.36 g/mol, Purity >99%. Potent, selective positive allosteric modulator for mGlu 1 (pEC 50 = 7.16 for rat mGlu 1a receptors). Increases basal mGluR 1 -induced cAMP accumulation and potentiates glutamate-induced cAMP accumulation. Selectively enhanced responses to DHPG in vivo ( EC 50 = 95 nM in CA3 neurons).
Key facts
CAS number:302841-89-0,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:325.36 g/mol,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biological description:Potent, selective positive allosteric modulator for mGlu1 (pEC50 = 7.16 for rat mGlu1a receptors). Increases basal mGluR1-induced cAMP accumulation and potentiates glutamate-induced cAMP accumulation. Selectively enhanced responses to DHPG in vivo (EC50= 95 nM in CA3 neurons).,
IUPAC Name:N-(9H-Xanthen-9-ylcarbonyl)carbamic acid butyl ester

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-The product can be stored for up to 12 months