Abcam, ab121214, Anti-SUSD2 antibody

Size: 100µL
Rabbit Polyclonal SUSD2 antibody. Suitable for IHC-P and reacts with Human samples. Cited in 5 publications. Immunogen corresponding to Recombinant Fragment Protein within Human SUSD2 aa 500-700.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human SUSD2 aa 500-700. The exact immunogen used to generate this antibody is proprietary information.Q9UGT4

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
SUSD2 also known as Sushi Domain Containing 2 is a protein involved in cellular activities such as cell adhesion and signaling. The protein has a molecular mass of approximately 80 kDa. SUSD2 expresses in various tissues including the brain lungs and reproductive organs. It often localizes at the cell membrane where it participates in interactions with other cellular components.
Biological function summary
This protein contributes to cellular communication and immune regulation. SUSD2 is a part of complexes that help mediate cell-to-cell interactions. These complexes play roles in the immune response influencing how the body responds to different stimuli. SUSD2 modulates activities such as phagocytosis and cell migration which are important in maintaining a healthy immune system.
Pathways
SUSD2 is involved in immune-related and cellular signaling pathways. It interacts with proteins like integrins and collagens which are involved in the extracellular matrix organization pathway. SUSD2 also participates in pathways related to immune regulation working together with proteins such as TNF-alpha and interleukins. This involvement is important for coordinating cellular responses necessary for immune defense.
SUSD2 possesses links to cancer and autoimmune diseases. Research indicates its possible involvement in certain cancer types like breast cancer where it might interact with oncogenes and tumor suppressors. SUSD2 also shows associations with autoimmune diseases possibly due to its role in immune system regulation. In cases such as rheumatoid arthritis it may interact with inflammatory cytokines contributing to disease pathology.