Abcam, ab121495, Anti-ODR4/TTG1 antibody

Size: 100µL
Rabbit Polyclonal ODR4/TTG1 antibody. Suitable for WB, ICC/IF, IHC-P and reacts with Mouse, Human samples. Cited in 3 publications. Immunogen corresponding to Recombinant Fragment Protein within Human ODR4 aa 300-450.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Mouse, Human,
Applications:WB, IHC-P, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human ODR4 aa 300-450. The exact immunogen used to generate this antibody is proprietary information.Q5SWX8

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
The ODR4/TTG1 protein sometimes referred to simply as TTG1 performs an important role in cellular processes and signal transduction. ODR4/TTG1 has a molecular mass of approximately 42 kDa. This protein is typically expressed in sensory neurons and other types of cells involved in chemosensory pathways. By interacting with elements of the cellular membrane ODR4/TTG1 facilitates signal processing and communication within cells which is essential for coordinating proper cell function.
Biological function summary
The protein ODR4/TTG1 influences hair and trichome development particularly in plants like Arabidopsis as it participates in the development of structures on the plant surface. It forms part of a complex interacting with Glabra1 and Transparent Testa Glabra2 proteins to regulate organ identity and epidermal cell differentiation. This regulatory action is essential for the correct formation and spacing of trichomes which are small hair-like projections on the surface of leaves and stems critical for plant defense.
Pathways
ODR4/TTG1 integrates into the signaling and developmental pathways that guide epidermal cell fate and differentiation. The protein plays a significant role in the well-established MYB-bHLH-WD40 transcriptional complex pathway which is pivotal in the regulation of gene expression patterns necessary for trichome development. Important proteins related through these pathways include the basic helix-loop-helix (bHLH) transcription factors which coordinate with ODR4/TTG1 to determine epidermal cell outcomes.
The role of ODR4/TTG1 extends to certain plant disorders related to defective trichome patterning or root hair development which can influence the plant's ability to interact with its environment. Issues with ODR4/TTG1 function affect the plant’s surface properties impacting interactions with pests and other environmental factors. Moreover the protein connects with Glabra1 through shared regulatory pathways linking to disorders affecting surface structures and consequently plant resilience against environmental stressors.