Abcam, ab121519, Anti-MCT 10 antibody

Size: 100µL
Rabbit Polyclonal MCT 10 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human SLC16A10 aa 450 to C-terminus.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human SLC16A10 aa 450 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q8TF71

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
MCT 10 also known as SLC16A10 is a member of the monocarboxylate transporter family. This transporter protein has a mass of approximately 58 kDa and facilitates the transport of aromatic amino acids across cell membranes. MCT 10 is mainly expressed in tissues like the small intestine liver kidney and placenta. It functions as a sodium-independent transporter which distinguishes it from other amino acid transporters that may rely on sodium gradients.
Biological function summary
MCT 10 plays a significant role in the cellular uptake and export of aromatic amino acids like tryptophan phenylalanine and tyrosine. These amino acids are essential precursors for the synthesis of important biological compounds. MCT 10 is not part of a larger protein complex but operates individually to facilitate these transport processes. Its function provides cells with necessary aromatic amino acids for various metabolic pathways and supports the body's metabolic needs.
Pathways
MCT 10 is a critical component in amino acid transport and metabolism. It is closely linked with pathways involving protein synthesis and neurotransmitter production. The transport activity of MCT 10 influences the concentration of precursor molecules for synthesis of proteins and neurotransmitters. MCT 10 works alongside other transporter proteins such as LAT1 within these metabolic pathways to ensure efficient cellular function and communication.
Impaired function of MCT 10 has been associated with certain inherited disorders of amino acid metabolism. These disorders can alter the normal balance of amino acids leading to metabolic complications. Aberrations in MCT 10 expression or function may also have implications in metabolic diseases and could affect related proteins like LAT1 which share similar transport duties and substrate specificities. Research on MCT 10 may unveil new insights into therapeutic targets for addressing disorders of amino acid metabolism.