Abcam, ab122512, Anti-C11orf96 antibody

Size: 100µL
Rabbit Polyclonal C11orf96 antibody. Suitable for IHC-P, ICC and reacts with Human samples. Cited in 2 publications. Immunogen corresponding to Recombinant Fragment Protein within Human C11orf96 aa 350 to C-terminus.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:ICC, IHC-PSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human C11orf96 aa 350 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q7Z7L8

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
C11orf96 also known as Chromosome 11 Open Reading Frame 96 is a protein-coding gene. The approximate mass of the C11orf96 protein is around 40 kDa. This protein exhibits higher expression levels in tissues such as the brain and heart. The detailed mechanical function of C11orf96 in cellular processes is not yet fully established. However it is categorized within the family of proteins with motifs that suggest potential interactions with other cellular molecules.
Biological function summary
The C11orf96 protein participates in cellular processes that are still under investigation. It may form part of a larger protein complex that influences cellular signaling and regulatory pathways. Its expression pattern hints at involvement in essential biological systems within specific tissues possibly contributing to neural and cardiac functions. Researchers speculate that disruptions in C11orf96 can affect cell signaling mechanisms impacting overall cell homeostasis.
Pathways
Current research suggests C11orf96 might play a role in the Wnt signaling pathway and could be linked to the modulation of gene expression. The Wnt pathway is important for regulating cell growth and development and proteins like beta-catenin may interact more directly within these networks. The specific involvement of C11orf96 in these pathways warrants further validation to define its precise biological contributions alongside these associated proteins.
C11orf96's expression patterns indicate potential links to neural development disorders and cardiac dysfunctions. Disorders such as autism spectrum disorders (ASD) and certain cardiomyopathies have shown associations in preliminary studies. The protein could interact with others like paxillin in the brain which play roles in synaptic connections and neurotransmission suggesting a pathway where disruptions might lead to ASD features. Further exploration is needed to confirm these associations and to identify possible therapeutic targets involving C11orf96.