Abcam, ab122677, Anti-C18orf32 antibody

Size: 100µL
Rabbit Polyclonal C18orf32 antibody. Suitable for IHC-P, ICC/IF and reacts with Human samples. Cited in 1 publication. Immunogen corresponding to Recombinant Fragment Protein within Human C18orf32 aa 1 to C-terminus.
Key facts
Host species:Rabbit,
Clonality:Polyclonal,
Isotype:IgG,
Carrier free:No,
Reacts with:Human,
Applications:IHC-P, ICC/IFSee reactivity dataSee the reactivity data table below for information on validated species and application combinations.,
Immunogen:Recombinant Fragment Protein within Human C18orf32 aa 1 to C-terminus. The exact immunogen used to generate this antibody is proprietary information.Q8TCD1

Properties and Storage Information:
Form-Liquid, Purification technique-Affinity purification Immunogen, Storage buffer-pH: 7.2Preservative: 0.02% Sodium azideConstituents: PBS, 40% Glycerol (glycerin, glycerine), Shipped at conditions-Blue Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions--20°C, Aliquoting information-Upon delivery aliquot, Storage information-Avoid freeze / thaw cycle

Supplementary Information:
This supplementary information is collated from multiple sources and compiled automatically.
C18orf32 also known as Chromosome 18 Open Reading Frame 32 is a protein-coding gene with limited characterization. It has a predicted mass of approximately 25 kDa and it expresses mainly in tissues such as the skeletal muscle heart and brain. The protein plays roles in cellular processes that scientists are still mapping in detail. Its expression levels and patterns suggest it may participate in specialized functions in specific tissues.
Biological function summary
C18orf32 appears to influence cellular functions linked to muscle and nerve physiology. It does not currently link to any specific protein complexes so the exact biological mechanisms remain under investigation. Researchers hypothesize that its role might include modulation of cellular responses or support of specific mitochondrial processes in myocytes or neurons due to its expression pattern.
Pathways
C18orf32 interacts within cellular frameworks that impact energy metabolism and neural communication. It potentially associates with pathways like ATP production or synaptic transmission processes although detailed maps of these pathways remain incomplete. Related proteins such as ATP synthase or synaptophysin could provide indirect interactions but more research needs to establish these connections definitively.
C18orf32 has associations with conditions affecting muscle or brain tissues like muscular dystrophy and neurodegenerative diseases. Mutations or malfunctions in this protein might link to disrupted energy management in muscle cells or synaptic dysfunctions in neurons possibly interacting with proteins such as dystrophin in muscular dystrophy or tau in neurodegenerative conditions. Further investigations aim to clarify C18orf32's implications in these diseases.