Abcam, ab141087, Monastrol, cell permeable mitosis inhibitor

Size: 10mg / 50mg
MW 292.36 Da, Purity >99%. A potent, cell-permeable, small molecule mitosis inhibitor. It arrests cells in mitosis and specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein required for mitotic spindle formation and maintenance (IC 50 = 14 μM).
Key facts
CAS number:329689-23-8,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:292.36 Da,
Molecular formula:C14H16N2O3S,
PubChem:2987927,
Nature:Synthetic,
Biochemical name:Monastrol,
Biological description:A potent, cell-permeable, small molecule mitosis inhibitor. It arrests cells in mitosis and specifically inhibits the motility of the mitotic kinesin Eg5, a motor protein required for mitotic spindle formation and maintenance (IC50 = 14 μM).,
Canonical smiles:CCOC(=O)C1=C(NC(=S)NC1C2=CC(=CC=C2)O)C,
InChi:InChI=1S/C14H16N2O3S/c1-3-19-13(18)11-8(2)15-14(20)16-12(11)9-5-4-6-10(17)7-9/h4-7,12,17H,3H2,1-2H3,(H2,15,16,20),
InChiKey:LOBCDGHHHHGHFA-UHFFFAOYSA-N,
IUPAC Name:ethyl 4-(3-hydroxyphenyl)-6-methyl-2-sulfanylidene-3,4-dihydro-1H-pyrimidine-5-carboxylate

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions