Abcam, ab141097, beta-Lapachone, Topoisomerase I inhibitor

Size: 10mg / 50mg
MW 244.28 Da, Purity >98%. Topoisomerase I inhibitor. Inhibits topoisomerase I induced DNA cleavage. Induces apoptosis via a p53 independent mechanism. Shows antitumor, antiviral, antibacterial, antifungal and wound healing activities.
Key facts
CAS number:132820-30-5,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:244.28 Da,
Molecular formula:C15H16O3,
PubChem:497540,
Nature:Synthetic,
Solubility:Soluble in ethanol to 50 mMSoluble in DMSO to 100 mM,
Biochemical name:2,2-Dimethyl-3,4,4a,10b-tetrahydrobenzo[h]chromene-5,6-dione,
Biological description:Topoisomerase I inhibitor. Inhibits topoisomerase I induced DNA cleavage. Induces apoptosis via a p53 independent mechanism. Shows antitumor, antiviral, antibacterial, antifungal and wound healing activities.,
Canonical smiles:CC1(CCC2C(O1)C3=CC=CC=C3C(=O)C2=O)C,
InChi:InChI=1S/C15H16O3/c1-15(2)8-7-11-13(17)12(16)9-5-3-4-6-10(9)14(11)18-15/h3-6,11,14H,7-8H2,1-2H3,
InChiKey:FGGFBHJNRSCDBK-UHFFFAOYSA-N,
IUPAC Name:2,2-dimethyl-3,4,4a,10b-tetrahydrobenzo[h]chromene-5,6-dione

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-+4°C, Appropriate long-term storage conditions-+4°C, Storage information-The product can be stored for up to 12 months