Abcam, ab141227, Apoptosis Activator 2 (AAII), Cytochrome c caspase activator and apoptosis inducer

Size: 10mg / 50mg
MW 306.1 Da, Purity >99%. Cell-permeable cytochrome c caspase activator. Promoting cytochrome-c dependent oligomerization of Apaf-1 into the mature apoptosome. Induces apoptosis in tumor cells (IC 50 = ~4 μM).
Key facts
CAS number:79183-19-0,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:306.1 Da,
Molecular formula:C15H9Cl2NO2,
PubChem:1901244,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:Apoptosis Activator 2,
Biological description:Cell-permeable cytochrome c caspase activator. Promoting cytochrome-c dependent oligomerization of Apaf-1 into the mature apoptosome. Induces apoptosis in tumor cells (IC50 = ~4 μM).,
Canonical smiles:C1=CC=C2C(=C1)C(=O)C(=O)N2CC3=CC(=C(C=C3)Cl)Cl,
InChi:InChI=1S/C15H9Cl2NO2/c16-11-6-5-9(7-12(11)17)8-18-13-4-2-1-3-10(13)14(19)15(18)20/h1-7H,8H2,
InChiKey:KGRJPLRFGLMQMV-UHFFFAOYSA-N,
IUPAC Name:1-[(3,4-dichlorophenyl)methyl]indole-2,3-dione

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions-Ambient, Appropriate long-term storage conditions-Ambient, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months