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BRAND / VENDOR: Abcam

Abcam, ab141305, CD 437, RARgamma-selective agonist.

CATALOG NUMBER: ab141305
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Product Description

Size: 10mg / 50mg
MW 398.5 Da, Purity >99%. Potent, cell-permeable RARγ-selective agonist (EC 50 values are 140, 28 and 7 nM for RAR-α, β and γ respectively). Shows RARγ-dependent and -independent effects on differentiation and apoptosis. Shows antitumor effects in vivo. .
Key facts
CAS number:125316-60-1,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:398.5 Da,
Molecular formula:C27H26O3,
PubChem:135411,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mMSoluble in ethanol to 10 mM,
Biochemical name:6-[3-(1-Adamantyl)-4-hydroxyphenyl]-2-naphthalenecarboxylic Acid,
Biological description:Potent, cell-permeable RARγ-selective agonist (EC50 values are 140, 28 and 7 nM for RAR-α, β and γ respectively). Shows RARγ-dependent and -independent effects on differentiation and apoptosis. Shows antitumor effects in vivo.,
Canonical smiles:C1C2CC3CC1CC(C2)(C3)C4=C(C=CC(=C4)C5=CC6=C(C=C5)C=C(C=C6)C(=O)O)O,
InChi:InChI=1S/C27H26O3/c28-25-6-5-22(20-1-2-21-11-23(26(29)30)4-3-19(21)10-20)12-24(25)27-13-16-7-17(14-27)9-18(8-16)15-27/h1-6,10-12,16-18,28H,7-9,13-15H2,(H,29,30),
InChiKey:LDGIHZJOIQSHPB-UHFFFAOYSA-N,
IUPAC Name:6-[3-(1-adamantyl)-4-hydroxyphenyl]naphthalene-2-carboxylic acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months


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