Abcam, ab141306, HA14-1, Bcl-2 inhibitor. BH-3 mimetic.

Size: 10mg / 50mg
MW 409.2 Da. Cell permeable Bcl-2 inhibitor. BH-3 mimetic. Disrupts Bax and Bcl-2 interactions. Apoptotic anticancer agent.
Key facts
CAS number:65673-63-4,
Form:SolidSee storage information,
Molecular weight:409.2 Da,
Molecular formula:C17H17BrN2O5,
PubChem:3549,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mMSoluble in ethanol to 100 mM,
Biochemical name:Ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate,
Biological description:Cell permeable Bcl-2 inhibitor. BH-3 mimetic. Disrupts Bax and Bcl-2 interactions. Apoptotic anticancer agent.,
Canonical smiles:CCOC(=O)C1=C(OC2=C(C1C(C#N)C(=O)OCC)C=C(C=C2)Br)N,
InChi:InChI=1S/C17H17BrN2O5/c1-3-23-16(21)11(8-19)13-10-7-9(18)5-6-12(10)25-15(20)14(13)17(22)24-4-2/h5-7,11,13H,3-4,20H2,1-2H3,
InChiKey:SXJDCULZDFWMJC-UHFFFAOYSA-N,
IUPAC Name:ethyl 2-amino-6-bromo-4-(1-cyano-2-ethoxy-2-oxoethyl)-4H-chromene-3-carboxylate

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months