Abcam, ab141409, Jasplakinolide, Actin polymerization and stabilization inducer

Size: 50µg
MW 709.7 Da, Purity >95%. Cell-permeable actin polymerization and stabilization inducer. Potent antiproliferative activity (IC 50 = 15 nM). Antitumor and antifungal agent. Active in vitro .
Key facts
CAS number:102396-24-7,
Purity:>95%,
Form:SolidSee storage information,
Source:Jaspis splendens,
Molecular weight:709.7 Da,
Molecular formula:C36H45BrN4O6,
PubChem:6436289,
Nature:Native,
Solubility:Soluble in DMSO,
Biochemical name:(4R,7R,10S,13R,15E,17R,19S)-7-[(2-bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone,
Biological description:Cell-permeable actin polymerization and stabilization inducer. Potent antiproliferative activity (IC50 = 15 nM). Antitumor and antifungal agent. Active in vitro.,
Canonical smiles:CC1CC(OC(=O)CC(NC(=O)C(N(C(=O)C(NC(=O)C(CC(=C1)C)C)C)C)CC2=C(NC3=CC=CC=C32)Br)C4=CC=C(C=C4)O)C,
Isomeric smiles:C[C@@H]\1C[C@@H](OC(=O)C[C@@H](NC(=O)[C@H](N(C(=O)[C@@H](NC(=O)[C@@H](C/C(=C1)/C)C)C)C)CC2=C(NC3=CC=CC=C32)Br)C4=CC=C(C=C4)O)C,
InChi:InChI=1S/C36H45BrN4O6/c1-20-15-21(2)17-23(4)47-32(43)19-30(25-11-13-26(42)14-12-25)40-35(45)31(18-28-27-9-7-8-10-29(27)39-33(28)37)41(6)36(46)24(5)38-34(44)22(3)16-20/h7-15,21-24,30-31,39,42H,16-19H2,1-6H3,(H,38,44)(H,40,45)/b20-15+/t21-,22+,23-,24-,30+,31+/m0/s1,
InChiKey:GQWYWHOHRVVHAP-HZIRKPFGSA-N,
IUPAC Name:(4R,7R,10S,13R,15E,17R,19S)-7-[(2-bromo-1H-indol-3-yl)methyl]-4-(4-hydroxyphenyl)-8,10,13,15,17,19-hexamethyl-1-oxa-5,8,11-triazacyclononadec-15-ene-2,6,9,12-tetrone

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months