Abcam, ab141438, AG 1478, EGF receptor tyrosine kinase inhibitor

Size: 1mg / 5mg / 25mg
MW 314.8 Da, Purity >98%. Selective EGF receptor tyrosine kinase inhibitor (K i = 10 nM). Supresses proliferation and cell-cycle progression. Cell-permeable and active in vivo .
Key facts
CAS number:175178-82-2,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:314.8 Da,
Molecular formula:C17H15ClN2O2,
PubChem:53429216,
Nature:Synthetic,
Solubility:Soluble in ethanol to 25 mMSoluble in DMSO to 100 mM,
Biochemical name:4-[(3-Chlorophenyl)methyl]-6,7-dimethoxyquinazoline,
Biological description:Selective EGF receptor tyrosine kinase inhibitor (Ki = 10 nM). Supresses proliferation and cell-cycle progression. Cell-permeable and active in vivo.,
Canonical smiles:COC1=C(C=C2C(=C1)C(=NC=N2)CC3=CC(=CC=C3)Cl)OC,
InChi:InChI=1S/C17H15ClN2O2/c1-21-16-8-13-14(7-11-4-3-5-12(18)6-11)19-10-20-15(13)9-17(16)22-2/h3-6,8-10H,7H2,1-2H3,
InChiKey:DOBKKEHYAFERJH-UHFFFAOYSA-N,
IUPAC Name:4-[(3-chlorophenyl)methyl]-6,7-dimethoxyquinazoline

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months