Abcam, ab141494, PKC412, Broad spectrum protein kinase inhibitor

Size: 1mg / 5mg
MW 570.6 Da, Purity >98%. Broad spectrum protein kinase inhibitor. Inhibits PKCα, PKCβ and PKCγ isoforms, PDFRβ, VEGFR2, Syk, PKC?, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. Antitumor activity. Active in vivo . .
Key facts
CAS number:120685-11-2,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:570.6 Da,
Molecular formula:C35H30N4O4,
PubChem:9829523,
Nature:Synthetic,
Solubility:Soluble in DMSO to 10 mM,
Biochemical name:Midostaurin,
Biological description:Broad spectrum protein kinase inhibitor. Inhibits PKCα, PKCβ and PKCγ isoforms, PDFRβ, VEGFR2, Syk, PKC?, Flk-1, Flt3, Cdk1/B, PKA, c-Kit, c-Fgr, c-Src, VEGFR1 and EGFR. Antitumor activity. Active in vivo.,
Canonical smiles:CC12C(C(CC(O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC,
Isomeric smiles:C[C@@]12[C@@H]([C@@H](C[C@@H](O1)N3C4=CC=CC=C4C5=C6C(=C7C8=CC=CC=C8N2C7=C53)CNC6=O)N(C)C(=O)C9=CC=CC=C9)OC,
InChi:InChI=1S/C35H30N4O4/c1-35-32(42-3)25(37(2)34(41)19-11-5-4-6-12-19)17-26(43-35)38-23-15-9-7-13-20(23)28-29-22(18-36-33(29)40)27-21-14-8-10-16-24(21)39(35)31(27)30(28)38/h4-16,25-26,32H,17-18H2,1-3H3,(H,36,40)/t25-,26-,32-,35+/m1/s1,
InChiKey:BMGQWWVMWDBQGC-IIFHNQTCSA-N,
IUPAC Name:N-[(2S,3R,4R,6R)-3-methoxy-2-methyl-16-oxo-29-oxa-1,7,17-triazaoctacyclo[12.12.2.12,6.07,28.08,13.015,19.020,27.021,26]nonacosa-8,10,12,14,19,21,23,25,27-nonaen-4-yl]-N-methylbenzamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months