Abcam, ab141520, Butyrolactone I, ATP-competitive cyclin-dependent kinase (CDK) inhibitor

Size: 200µg / 1mg / 5mg
MW 424.4 Da, Purity >97%. Cell permeable, selective, ATP-competitive CDK inhibitor. Inhibits CDC2, CDK2, and CDK5. Inhibits the cell cycle at G1/S and G2/M. Apoptotic and antitumor activity.
Key facts
CAS number:87414-49-1,
Purity:>97%,
Form:SolidSee storage information,
Molecular weight:424.4 Da,
Molecular formula:C24H24O7,
PubChem:51340302,
Nature:Synthetic,
Solubility:Soluble in DMSO to 10 mMSoluble in ethanol to 50 mM,
Biochemical name:Butyrolactonei,
Biological description:Cell permeable, selective, ATP-competitive CDK inhibitor. Inhibits CDC2, CDK2, and CDK5. Inhibits the cell cycle at G1/S and G2/M. Apoptotic and antitumor activity.,
Canonical smiles:CC(=CCC1=C(C=CC(=C1)CC2(C(=C(C(=O)O2)O)C3=CC=C(C=C3)O)C(=O)OC)O)C,
Isomeric smiles:CC(=CCC1=C(C=CC(=C1)C[C@]2(C(=C(C(=O)O2)O)C3=CC=C(C=C3)O)C(=O)OC)O)C,
InChi:InChI=1S/C24H24O7/c1-14(2)4-6-17-12-15(5-11-19(17)26)13-24(23(29)30-3)20(21(27)22(28)31-24)16-7-9-18(25)10-8-16/h4-5,7-12,25-27H,6,13H2,1-3H3/t24-/m0/s1,
InChiKey:NGOLMNWQNHWEKU-DEOSSOPVSA-N,
IUPAC Name:methyl (2S)-4-hydroxy-2-[[4-hydroxy-3-(3-methylbut-2-enyl)phenyl]methyl]-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylate

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months