Abcam, ab141588, QNZ, NF-kB inhibitor

Size: 1mg
MW 358.4 Da, Purity >98%. Potent, selective NF-kB inhibitor (IC 50 = 11 nM). Inhibits LPS-induced TNFα production (IC 50 = 7 nM). Reduces edema in inflammation in vivo. .
Key facts
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:358.4 Da,
Molecular formula:C22H22N4O,
PubChem:35026803,
Nature:Synthetic,
Solubility:Soluble in DMSO to 50 mMSoluble in ethanol to 25 mM,
Biochemical name:N4-[2-(4-phenoxyphenyl)ethyl]-1,2-dihydroquinazoline-4,6-diamine,
Biological description:Potent, selective NF-kB inhibitor (IC50 = 11 nM). Inhibits LPS-induced TNFα production (IC50 = 7 nM). Reduces edema in inflammation in vivo.,
Canonical smiles:C1NC2=C(C=C(C=C2)N)C(=N1)NCCC3=CC=C(C=C3)OC4=CC=CC=C4,
InChi:InChI=1S/C22H22N4O/c23-17-8-11-21-20(14-17)22(26-15-25-21)24-13-12-16-6-9-19(10-7-16)27-18-4-2-1-3-5-18/h1-11,14,25H,12-13,15,23H2,(H,24,26),
InChiKey:GGBVTWRQPMDRCK-UHFFFAOYSA-N,
IUPAC Name:4-N-[2-(4-phenoxyphenyl)ethyl]-1,2-dihydroquinazoline-4,6-diamine

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months