Abcam, ab141622, Chaetomellic acid A, farnesyltransferase inhibitor

Size: 5mg / 25mg
MW 326.5 Da, Purity >98%. Potent, selective, competitive farnesyltransferase inhibitor (IC 50 = 55 nM). Inhibits geranylgeranyltransferase I and II and protein prenyltransferase (IC 50 values are 92, 34 and 17 μM respectively). Blocks Ha-Ras signalling. Active in vivo .
Key facts
CAS number:148796-51-4,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:326.5 Da,
Molecular formula:C19H34O4,
PubChem:3037595,
Nature:Synthetic,
Biochemical name:Chaetomellic acid A,
Biological description:Potent, selective, competitive farnesyltransferase inhibitor (IC50 = 55 nM). Inhibits geranylgeranyltransferase I and II and protein prenyltransferase (IC50 values are 92, 34 and 17 μM respectively). Blocks Ha-Ras signalling. Active in vivo.,
Canonical smiles:CCCCCCCCCCCCCCC(=C(C)C(=O)O)C(=O)O,
Isomeric smiles:CCCCCCCCCCCCCC/C(=C(\C)/C(=O)O)/C(=O)O,
InChi:InChI=1S/C19H34O4/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-17(19(22)23)16(2)18(20)21/h3-15H2,1-2H3,(H,20,21)(H,22,23)/b17-16-,
InChiKey:ULSDRNDLXFVDED-MSUUIHNZSA-N,
IUPAC Name:(Z)-2-methyl-3-tetradecylbut-2-enedioic acid

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions|The product can be stored for up to 12 months