Abcam, ab142049, AZD1152-HQPA, Aurora B kinase inhibitor

Size: 5mg / 25mg
MW 507.6 Da, Purity >99%. Potent, selective Aurora B kinase inhibitor (IC 50 = 0.37 nM). Induces apoptosis in vitro . Antitumor agent. Cell-permeable. Active in vitro and in vivo .
Key facts
CAS number:722544-51-6,
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:507.6 Da,
Molecular formula:C26H30FN7O3,
PubChem:16007391,
Nature:Synthetic,
Solubility:Soluble in DMSO to 25 mM,
Biochemical name:Azd-1152hqpa,
Biological description:Potent, selective Aurora B kinase inhibitor (IC50 = 0.37 nM). Induces apoptosis in vitro. Antitumor agent. Cell-permeable. Active in vitro and in vivo.,
Canonical smiles:CCN(CCCOC1=CC2=C(C=C1)C(=NC=N2)NC3=NNC(=C3)CC(=O)NC4=CC(=CC=C4)F)CCO,
InChi:InChI=1S/C26H30FN7O3/c1-2-34(10-11-35)9-4-12-37-21-7-8-22-23(16-21)28-17-29-26(22)31-24-14-20(32-33-24)15-25(36)30-19-6-3-5-18(27)13-19/h3,5-8,13-14,16-17,35H,2,4,9-12,15H2,1H3,(H,30,36)(H2,28,29,31,32,33),
InChiKey:QYZOGCMHVIGURT-UHFFFAOYSA-N,
IUPAC Name:2-[3-[[7-[3-[ethyl(2-hydroxyethyl)amino]propoxy]quinazolin-4-yl]amino]-1H-pyrazol-5-yl]-N-(3-fluorophenyl)acetamide

Product details:
This product is manufactured by BioVision, an Abcam company and was previously called 1583 Aurora Kinase B Inhibitor (AZD1152-HQPA). 1583-25 is the same size as the 25 mg size of ab142049.

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months