Abcam, ab142050, Dasatinib, Src family tyrosine kinase (SFK)/Bcl-Abl kinase inhibitor

Size: 5mg / 25mg
MW 488 Da, Purity >98%. Potent Src family tyrosine kinase (SFK)/Bcl-Abl kinase inhibitor.Inhibits growth of Bcr-Abl–dependent chronic myeloid leukemia xenografts in nude mice. Anti-tumor activity *in vivo*.
Key facts
CAS number:302962-49-8,
Purity:>98%,
Form:SolidSee storage information,
Molecular weight:488 Da,
Molecular formula:C22H26ClN7O2S,
PubChem:3062316,
Nature:Synthetic,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:Dasatinib,
Biological description:Potent Src family tyrosine kinase (SFK)/Bcl-Abl kinase inhibitor.Inhibits growth of Bcr-Abl–dependent chronic myeloid leukemia xenografts in nude mice. Anti-tumor activity *in vivo*.,
Canonical smiles:CC1=C(C(=CC=C1)Cl)NC(=O)C2=CN=C(S2)NC3=CC(=NC(=N3)C)N4CCN(CC4)CCO,
InChi:InChI=1S/C22H26ClN7O2S/c1-14-4-3-5-16(23)20(14)28-21(32)17-13-24-22(33-17)27-18-12-19(26-15(2)25-18)30-8-6-29(7-9-30)10-11-31/h3-5,12-13,31H,6-11H2,1-2H3,(H,28,32)(H,24,25,26,27),
InChiKey:ZBNZXTGUTAYRHI-UHFFFAOYSA-N,
IUPAC Name:N-(2-chloro-6-methylphenyl)-2-[[6-[4-(2-hydroxyethyl)piperazin-1-yl]-2-methylpyrimidin-4-yl]amino]-1,3-thiazole-5-carboxamide

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions