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BRAND / VENDOR: Abcam

Abcam, ab142138, Nimbolide, CyclinA and ERK1/2 inhibitor

CATALOG NUMBER: ab142138
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Product Description

Size: 5mg / 25mg
MW 466.5 Da, Purity >97%. CyclinA and ERK1/2 inhibitor. Terpenoid lactone derived from Azadirachta indica . Proapoptotic and anticancer activity in vivo .
Key facts
CAS number:25990-37-8,
Purity:>97%,
Form:SolidSee storage information,
Source:Azadirachta indica,
Molecular weight:466.5 Da,
Molecular formula:C27H30O7,
PubChem:100017,
Nature:Native,
Solubility:Soluble in DMSO to 100 mM,
Biochemical name:Methyl 2-[6-(furan-3-yl)-7,9,11,15-tetramethyl-12,16-dioxo-3,17-dioxapentacyclo[9.6.1.02,9.04,8.015,18]octadeca-7,13-dien-10-yl]acetate,
Biological description:CyclinA and ERK1/2 inhibitor. Terpenoid lactone derived from Azadirachta indica. Proapoptotic and anticancer activity in vivo.,
Canonical smiles:CC1=C2C(CC1C3=COC=C3)OC4C2(C(C5(C6C4OC(=O)C6(C=CC5=O)C)C)CC(=O)OC)C,
InChi:InChI=1S/C27H30O7/c1-13-15(14-7-9-32-12-14)10-16-20(13)27(4)17(11-19(29)31-5)26(3)18(28)6-8-25(2)22(26)21(23(27)33-16)34-24(25)30/h6-9,12,15-17,21-23H,10-11H2,1-5H3,
InChiKey:JZIQWNPPBKFOPT-UHFFFAOYSA-N,
IUPAC Name:methyl 2-[6-(furan-3-yl)-7,9,11,15-tetramethyl-12,16-dioxo-3,17-dioxapentacyclo[9.6.1.02,9.04,8.015,18]octadeca-7,13-dien-10-yl]acetate

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months


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Collaboration

Tony Tang

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