Abcam, ab142140, ISO 1, MIF-Antagonist, MIF antagonist

Size: 5mg
MW 235.24 Da, Purity >99%. Potent, cell-permeable MIF (migration inhibitory factor) antagonist (IC 50 = 25 μM). Targets catalytic pocket of MIF. Inhibits TNF release from macrophages. Anti-inflammatory. Active in vitro and in vivo .
Key facts
Purity:>99%,
Form:SolidSee storage information,
Molecular weight:235.24 Da,
Molecular formula:C12H13NO4,
PubChem:6098948,
Nature:Synthetic,
Solubility:Soluble in ethanol to 100 mMSoluble in DMSO to 100 mM,
Biochemical name:CID 6098948,
Biological description:Potent, cell-permeable MIF (migration inhibitory factor) antagonist (IC50 = 25 μM). Targets catalytic pocket of MIF. Inhibits TNF release from macrophages. Anti-inflammatory. Active in vitro and in vivo.,
Canonical smiles:COC(=O)CC1CC(=C2C=CC(=O)C=C2)NO1,
Isomeric smiles:COC(=O)CC1CC(=C2C=CC(=O)C=C2)NO1,
InChi:InChI=1S/C12H13NO4/c1-16-12(15)7-10-6-11(13-17-10)8-2-4-9(14)5-3-8/h2-5,10,13H,6-7H2,1H3,
InChiKey:CLVQGFPQFNASJH-UHFFFAOYSA-N,
IUPAC Name:methyl 2-[3-(4-oxocyclohexa-2,5-dien-1-ylidene)-1,2-oxazolidin-5-yl]acetate

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-Store under desiccating conditions, The product can be stored for up to 12 months