Abcam, ab142780, Rhod-2 AM, fluorescent Ca2+ indicator

Size: 1mg
Rhod-2 AM (ab142780) is a cell-permeable fluorescent Ca2+ indicator. Binds to Ca2+ (Kd = 570 nM) and fluoresces yellow/orange upon calcium binding. Molecular weight (MW): 1123.9; Purity > 93% - Suitable to investigate changes in intracellular free Ca2+ concentration - Excitation/Emission: 552 nm/ 581 nm - Cited in over 20 publications
Key facts
CAS number:145037-81-6,
Purity:>93%,
Form:SolidSee storage information,
Molecular weight:1123.9 Da,
Molecular formula:C52H59BrN4O19,
PubChem:25229581,
Nature:Synthetic,
Solubility:Soluble in DMSO to 1 mg/ml,
Biochemical name:Rhod-2 AM,
Biological description:Cell-permeable fluorescent Ca2+ indicator. Binds to Ca2+ (Kd = 570 nM) and fluoresces yellow/orange upon Ca2+ binding. Cell-impermeable form, Rhod-2 K+ salt (ab142781) also available. Ex550/Em578.,
Canonical smiles:CC1=CC(=C(C=C1)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C)OCCOC2=C(C=CC(=C2)C3=C4C=CC(=[N+](C)C)C=C4OC5=C3C=CC(=C5)N(C)C)N(CC(=O)OCOC(=O)C)CC(=O)OCOC(=O)C.[Br-],
InChi:InChI=1S/C52H59N4O19.BrH/c1-32-10-16-42(55(24-48(61)71-28-67-33(2)57)25-49(62)72-29-68-34(3)58)46(20-32)65-18-19-66-47-21-37(11-17-43(47)56(26-50(63)73-30-69-35(4)59)27-51(64)74-31-70-36(5)60)52-40-14-12-38(53(6)7)22-44(40)75-45-23-39(54(8)9)13-15-41(45)52;/h10-17,20-23H,18-19,24-31H2,1-9H3;1H/q+1;/p-1,
InChiKey:RWXWZOWDWYQKBK-UHFFFAOYSA-M,
IUPAC Name:[9-[4-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-3-[2-[2-[bis[2-(acetyloxymethoxy)-2-oxoethyl]amino]-5-methylphenoxy]ethoxy]phenyl]-6-(dimethylamino)xanthen-3-ylidene]-dimethylazanium;bromide,
Excitation/Emission:Ex: 552nm, Em: 581nm

Product details:
The Ester Rhod-2 once hydrolyzed by cellular endogenous esterases will bind Ca2+ and localizes to mitochondria,

Properties and Storage Information:
Shipped at conditions-Ambient - Can Ship with Ice, Appropriate short-term storage conditions--20°C, Appropriate long-term storage conditions--20°C, Storage information-It is important to note that this product is reported to be light sensitive, Store in the dark, Store under desiccating conditions